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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Prev Med. 2021 May 19;150:106626. doi: 10.1016/j.ypmed.2021.106626

Table 3.

Isotemporal associations for substitutions in activity with cardiovascular risk and functional burden

Substitution of one SD* of activity at baseline (n=1648)

OR (95% CI)

Replace ST with 84 mins of LPA Replace ST with 24 mins of MVPA Replace LPA with 24 mins of MVPA
Cardiovascular risk and functional burden 0.94 (0.83, 1.06) 0.85 (0.75, 0.96) 0.86 (0.75, 0.99)
Substitution of one SD* change in activity from baseline to 10-year follow-upb (n=759)

OR (95% CI)

Replace ST with 84 mins of LPA Replace ST with 24 mins of MVPA Replace LPA with 24 mins of MVPA

Cardiovascular risk and functional burden 1.02 (0.84, 1.24) 0.62 (0.49, 0.79) 0.62 (0.48, 0.79)

Models adjusted for 2 activities (besides activity being replaced) age, sex, race, study center, education, health insurance, employment status, smoking status, alcohol consumption, drinking status, sleep quality, and total wear time;

b

10-year change models also adjusted for baseline ST and MVPA;

ST: sedentary time; LPA: light intensity physical activity; MVPA: moderate to vigorous intensity physical activity; SD: Standard Deviation; mins: minutes;

*

1 SD of LPA: 84 minutes; 1 SD of MVPA: 24 minutes