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. 2021 Sep 2;100(12):101462. doi: 10.1016/j.psj.2021.101462

Table 7.

Effect of dietary Zn on the tight junction related gene expression in jejunum of ducks challenged with LPS.

Zinc level 0 30 120 0 30 120 SEM Main effect Zn level
LPS
P-value
LPS - - - + + + 0 30 120 - + Zn level LPS Interaction
CLDN-1 1.00c 1.27b 1.50a 0.66d 0.80d 1.33b 0.083 0.83c 1.03b 1.41a 1.26a 0.93b <0.001 <0.001 0.046
CLDN-2 1.01 0.84 0.85 1.32 1.22 0.92 0.040 1.12a 1.04b 0.81b 0.90b 1.08a 0.001 <0.001 0.084
OCLD 1.01 1.20 1.44 0.73 0.85 1.34 0.045 0.87c 1.02b 1.39a 1.27a 0.97b <0.001 <0.001 0.163
ZO-1 1.01c 1.25b 1.67a 0.68d 1.18b 1.56c 0.052 0.84c 1.21b 1.62a 1.31a 1.14b <0.001 <0.001 0.029
ZO-2 1.00 1.06 1.11 0.93 1.04 1.02 0.028 0.97 1.05 1.07 1.06 1.00 0.291 0.264 0.846
ZO-3 1.01 1.49 1.63 0.69 1.17 1.46 0.050 0.85c 1.33b 1.55a 1.37a 1.11b <0.001 <0.001 0.208
EPCAM 1.01 1.07 1.10 0.75 0.94 0.95 0.030 0.88 1.00 1.02 1.06a 0.88b 0.068 0.002 0.594
JAM2 1.01 1.19 1.08 0.81 0.84 1.06 0.032 0.91 1.02 1.07 1.10a 0.90b 0.063 0.001 0.067
JAM3 1.00 1.11 1.10 0.89 0.98 1.07 0.031 0.95 1.05 1.09 1.07 0.98 0.187 0.148 0.831
MLCK 1.01d 0.76d 0.65d 3.95a 3.50b 2.31c 0.198 2.48a 2.13b 1.48c 0.81b 3.25a <0.001 <0.001 <0.001

Abbreviations: CLDN-1, claudin1; CLDN-2, claudin 2; EPCAM, epithelial cell adhesion molecule; JAM2, junctional adhesion molecule-2; JAM3, junctional adhesion molecule-3; MLCK, myosin light-chain kinase; OCLD, occluding; ZO-1, zonula occludens-1; ZO-2, zonula occludens-2; ZO-3, zonula occludens-3.

a-d

Mean values in a row without common superscript are significantly different (P < 0.05) (n = 8).