Table 9.
Zinc level | 0 | 30 | 120 | 0 | 30 | 120 | SEM | Main effect | Zn level |
LPS |
P-value |
|||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LPS | - | - | - | + | + | + | 0 | 30 | 120 | - | + | Zn level | LPS | Interaction | ||
IL-2 | 1.01d | 1.10d | 0.96d | 4.45a | 3.50b | 2.79c | 0.219 | 2.73a | 2.30ab | 1.88b | 1.02b | 3.58a | 0.003 | <0.001 | 0.005 | |
IL-6 | 1.00c | 1.10c | 0.91c | 3.54a | 3.85a | 2.73b | 0.187 | 2.27a | 2.48a | 1.82b | 1.01b | 3.37a | <0.001 | <0.001 | 0.003 | |
IL-8 | 1.00c | 1.11c | 1.13c | 2.83a | 2.23b | 2.09b | 0.110 | 1.92a | 1.67b | 1.61b | 1.08b | 2.38a | 0.020 | <0.001 | 0.001 | |
IL-10 | 1.01c | 1.21c | 1.25c | 2.40b | 2.53b | 3.38a | 0.134 | 1.70b | 1.87b | 2.32a | 1.16b | 2.77a | <0.001 | <0.001 | 0.002 | |
INF-α | 1.01 | 1.15 | 1.22 | 1.02 | 0.93 | 1.02 | 0.096 | 1.02 | 1.04 | 1.12 | 1.12 | 0.99 | 0.902 | 0.509 | 0.877 | |
INF-β | 1.01 | 1.05 | 1.02 | 1.15 | 1.05 | 1.09 | 0.022 | 1.08 | 1.05 | 1.06 | 1.03 | 1.10 | 0.860 | 0.111 | 0.381 | |
INF-γ | 1.01c | 1.12c | 1.07c | 2.38a | 1.91b | 1.75b | 0.086 | 1.69a | 1.52b | 1.41b | 1.07b | 2.02a | 0.046 | <0.001 | 0.008 | |
TNF-α | 1.01d | 1.14d | 0.93d | 2.73a | 2.43b | 2.07c | 0.112 | 1.87a | 1.78a | 1.50b | 1.03b | 2.41a | 0.001 | <0.001 | 0.015 | |
TLR4 | 1.01c | 1.03c | 1.07c | 4.60a | 4.17a | 3.43b | 0.234 | 2.81a | 2.60a | 2.25b | 1.04b | 4.07a | 0.003 | <0.001 | 0.001 | |
iNOS | 1.00c | 0.89c | 0.73c | 2.84a | 2.01b | 1.72b | 0.113 | 1.92a | 1.45b | 1.23c | 0.87b | 2.19a | <0.001 | <0.001 | <0.001 | |
Caspase-3 | 1.00d | 0.98d | 1.05d | 4.58a | 3.61b | 2.87c | 0.216 | 2.79a | 2.30b | 1.96c | 1.01b | 3.69a | <0.001 | <0.001 | <0.001 | |
Caspase-8 | 1.00d | 1.14d | 1.06d | 3.13a | 2.50b | 1.92c | 0.129 | 2.07a | 1.82a | 1.49b | 1.07b | 2.52a | <0.001 | <0.001 | <0.001 |
Abbreviations: IL-2, interleukin 2; IL-6, interleukin 6; IL-8, interleukin 8; IL-10, interleukin 10; INFα, interferon-α; INFβ, interferon-β; INFγ, interferon-γ; iNOS, inducible nitric oxide synthase; TNFα, tumor necrosis factor-α; TLR4, Toll-like receptor 4.
Mean values in a row without common superscript are significantly different (P < 0.05) (n = 8).