. 2021 Sep 2;100(12):101462. doi: 10.1016/j.psj.2021.101462

Table 10.

Effect of Zn levels on the inflammatory response gene expression of DIECs challenged with LPS.

Zinc level	TPEN	CON	ZINC	TPEN	CON	ZINC	SEM		Zn level			LPS		P-value
LPS	-	-	-	+	+	+		Main effect	TPEN	CON	ZINC	-	+	Zn level	LPS	Interaction
IL-2	1.38^c	1.01^c	0.81^c	4.68^a	2.75^b	3.11^b	0.215		3.03^a	1.88^b	1.96^b	1.06^b	3.52^a	<0.001	<0.001	0.001
IL-6	2.29	1.01	0.93	4.77	3.84	2.95	0.214		3.53^a	2.46^b	1.94^c	1.41^b	3.86^a	<0.001	<0.001	0.062
IL-8	1.36	1.00	0.94	4.03	3.23	2.96	0.186		2.69^a	2.17^b	1.92^b	1.10^b	3.38^a	<0.001	<0.001	0.062
IL-10	1.20^c	1.01^c	1.15^c	2.58^b	2.27^b	3.47^a	0.145		1.89^b	1.64^b	2.31^a	1.12^b	2.78^a	<0.001	<0.001	0.003
INF-γ	1.67^d	1.01^e	0.89^e	3.46^a	2.89^b	2.10^c	0.14		2.57^a	1.95^b	1.50^c	1.19^b	2.81^a	<0.001	<0.001	0.001
TNF-α	2.15^c	1.01^e	0.88^e	4.29^a	3.12^b	1.63^d	0.182		3.22^a	2.06^b	1.25^c	1.35^b	3.01^a	<0.001	<0.001	<0.001
iNOS	15.99^b	1.01^d	0.86^d	20.57^a	3.28^c	2.08^cd	1.175		18.28a	2.14^b	1.47^c	5.95^b	8.65^a	<0.001	<0.001	0.015
TLR4	1.40^c	1.01^c	1.12^c	4.32^a	3.94^a	2.81^b	0.203		2.86^a	2.48^b	1.96^c	1.18^b	3.69^a	<0.001	<0.001	<0.001

Abbreviations: IL-2, interleukin 2; IL-6, interleukin 6; IL-8, interleukin 8; IL-10, interleukin 10; INFγ, interferon-γ; iNOS, inducible nitric oxide synthase; TNFα, tumor necrosis factor-α; TLR4, Toll-like receptor 4.

^a-e

Mean values (n = 8) in a row without common superscript are significantly different (n = 8) (P < 0.05).