Table 1.
Demographics of study samples
| Cohort | Diagnosis | N | Female (%) | Age at blood sample collection, mean (SD) | RIN, mean (SD) |
|---|---|---|---|---|---|
| ADNI (N = 661) | CN | 213 | 107 (50%) | 76.4 (6.4) | 6.91 (0.51) |
| MCI | 345 | 144 (42%) | 73.2 (7.9) | 6.98 (0.55) | |
| AD | 103 | 38 (37%) | 77.6 (7.8) | 6.98 (0.64) | |
| AddNeuroMed (N = 674) | CN | 243 | 147 (60%) | 74.2 (6.6) | 8.96 (0.73) |
| MCI | 208 | 120 (58%) | 75.5 (6.5) | 8.50 (0.59) | |
| AD | 223 | 146 (65%) | 76.8 (6.8) | 8.43 (0.64) |
The table was modified from a previous study [51]
Abbreviations: AD Alzheimer’s disease; CN cognitively normal older adults; MCI mild cognitive impairment; RIN RNA integrity number; SD standard deviation