Fig. 1.

Classification of ISWI family. Molecular components, functional domains, subcellular localization and targeting inhibitors for the ISWI family. A Sixteen different types of ISWI complexes are shown [14, 22, 48]. They harbor either SMARCA1 or SMARCA5 as ATPase subunits and 1–3 noncatalytic subunits. B Schematic representation of functional domains, protein subcellular localization, number of nucleotides and targeting inhibitors for each ISWI protein member