Fig. 3.

Relevance between the short-chain fatty acid content in the brain and the gut microbiome. a Levels of SCFAs in the serum. b Levels of SCFAs in the brain. c Matrix is used to describe SCFA–microbe correlations. The depth of the color of the square indicates the magnitude of the correlation, where blue squares represent positive correlations and red squares represent negative correlations. White asterisks indicate the significance of the correlation (*q < 0.1, **q < 0.05). In a and b, black asterisks indicate the significance of the correlation *P < 0.05, **P < 0.01, ***P < 0.001 vs. the CON group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 vs. the CUMS group