Fig. 1.

Summary of the associations examined. a Schematic representation of the mediated association between the maternal SBP-increasing genetic score and offspring birth weight, and a summary of association analyses. b Schematic representation of the association between the maternal SBP-increasing genetic score and fetal growth velocity, and a summary of an association analysis. G, genetic score as an exposure; M, mediator as an intermediate phenotype; Y, outcome; C, confounder; PGS, polygenic score; SBP, systolic blood pressure; BMI, body mass index