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Observed and PAVA-Adjusted Response in Group RS
| Assigned Dose (mg) | Number of Successes | Number of Patients | Observed Response Rate (%) |
PAVA-adjusted Response Rate(%) |
|---|---|---|---|---|
| 10.5 | 1 | 3 | 0.333 | 0.333 |
| 12 | 28 | 29 | 0.966 | 0.966 |
| 13.5 | 8 | 8 | 1.000 | 1.000 |
PAVA-adjusted response rates were estimated using the weighted isotonic regression method
PAVA pooled-adjacent-violators algorithm
