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Observed and PAVA-Adjusted Response in Group R
| Assigned Dose (mg) | Number of Successes | Number of Patients | Observed Response Rate (%) |
PAVA-adjusted Response Rate(%) |
|---|---|---|---|---|
| 12 | 0 | 1 | 0.000 | 0.000 |
| 13.5 | 4 | 7 | 0.571 | 0.571 |
| 15 | 25 | 26 | 0.962 | 0.962 |
| 16.5 | 6 | 6 | 1.000 | 1.000 |
PAVA-adjusted response rates were estimated using the weighted isotonic regression method
PAVA pooled-adjacent-violators algorithm
