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. 2021 Nov 4;21:1135. doi: 10.1186/s12879-021-06824-y

Table 2.

Comparison of underlying diseases in COVID-19 patients with GI or respiratory symptoms

Variable Total GIA (n = 92) RA (n = 184) GIR (n = 151) WGIR (n = 80) P-value*
N (%) N (%) N (%) N (%) N (%)
Chronic cardiovascular disease 60 (11.8) 16 (17.4) 23 (12.5) 11 (7.3) 10 (12.5) 0.120
Hypertension 128 (25.3) 28 (30.4) 43 (23.5) 35 (23.2) 22 (27.5) 0.539
Hyperthyroidism 1 (0.2) 0 (0) 1 (0.5) 0 (0) 0 (0) 1.000
Hypothyroidism 13 (2.6) 2 (2.2) 5 (2.7) 5 (3.3) 1 (1.3) 0.868
G6PD deficiency 5 (1.0) 0 (0) 2 (1.1) 0 (0) 3 (3.8) 0.025
Hyperlipidemia 30 (5.9) 6 (6.5) 13 (7.1) 9 (6.0) 2 (2.5) 0.537
Malignant neoplasm 8 (1.6) 5 (5.4) 0 (0) 3 (2.0) 0 (0) 0.003
Chronic hematologic disease 9 (1.8) 2 (2.2) 3 (1.6) 2 (1.3) 2 (2.5) 0.845
Chronic neurologic disorder 17 (3.4) 4 (4.3) 5 (2.7) 5 (3.3) 3 (3.8) 0.869
Obesity 0 (0) 3 (1.6) 0 (0) 0 (0) 0 (0) 0.268
Chronic pulmonary disease 12 (2.4) 4 (4.3) 4 (2.2) 3 (2.0) 1 (1.3) 0.608
Diabetes 116 (22.9) 24 (26.1) 46 (25.0) 24 (15.9) 22 (27.5) 0.090
Asthma 27 (5.3) 3 (3.3) 15 (8.2) 6 (4.0) 3 (3.8) 0.264
Chronic kidney disease 29 (5.7) 9 (9.8) 7 (3.8) 6 (4.0) 7 (8.8) 0.099
Rheumatologic disorder 7 (1.4) 1 (1.1) 0 (0) 2 (1.3) 4 (5.0) 0.015
Liver disease 10 (2.0) 6 (6.5) 1 (0.5) 1 (0.7) 2 (2.5) 0.005

RA respiratory alone, GIA gastrointestinal alone, GIR gastrointestinal and respiratory, WGIR without gastrointestinal or respiratory, N number, G6PD glucose-6-phosphate dehydrogenase

*Analyzed by Chi-squared test

Analyzed by Fisher’s exact test