Table 1.
Baseline Characteristics of Study Cohort by Treatment Arm
| Oxytocin | Placebo | P value* | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age, y | 68.3 | 5.8 | 66.3 | 4.8 | .44 |
| Sex, male | 41.7% | 11.1% | .15 | ||
| Ethnic group, Latino | 8.3% | 11.1% | .69 | ||
| Body weight, kg | 105.7 | 16.6 | 93.9 | 10.4 | .19 |
| Body mass index, kg/m2 | 36.8 | 3.5 | 36.8 | 3.6 | 1.00 |
| Waist circumference, cm | 117.9 | 10.2 | 116.5 | 9.1 | .50 |
| Fasting glucose, mg/dL | 91.9 | 9.0 | 92.0 | 8.8 | .97 |
| 2-hour glucose, mg/dL | 150.4 | 34.9 | 148.3 | 44.7 | .71 |
| Hemoglobin A1c, % | 5.7 | 0.3 | 5.7 | 0.5 | .65 |
| Total cholesterol, mg/dL | 195.7 | 50.1 | 177.0 | 42.2 | .43 |
| High-density lipoprotein, mg/dL | 45.8 | 9.6 | 50.3 | 12.6 | .50 |
| Low-density lipoprotein, mg/dL | 123.8 | 43.6 | 95.9 | 35.1 | .24 |
| Triglycerides, mg/dL | 128.9 | 49.9 | 154.8 | 114.2 | .82 |
| Appetite, score | 31.0 | 1.8 | 29.6 | 4.0 | .34 |
| CES-D, score | 3.9 | 3.3 | 5.4 | 4.5 | .44 |
| MOCA, score | 27.3 | 2.5 | 28.1 | 2.8 | .43 |
| SPPB, score | 9.3 | 2.3 | 9.1 | 1.5 | .89 |
| Timed Up and Go, seconds | 11.9 | 3.6 | 12.2 | 2.7 | .52 |
| Fat mass, kg | 47.9 | 6.2 | 43.6 | 7.6 | .44 |
| Lean mass, kg | 54.0 | 13.9 | 46.8 | 6.9 | .40 |
| Fat, % | 156.2 | 110.4 | 143.4 | 107.9 | 1.00 |
| Serum osmolality, mOsm/kg | 327.27 | 107.20 | 292.33 | 5.39 | .27 |
CES-D, Centers for Epidemiologic Studies Depression scale; MOCA, Montreal Cognitive Assessment.
*
Wilcoxon Test for independent samples was used for the comparison of continuous variables; Fisher exact test was used for comparison of binary variables.