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. 2021 Oct 21;11:730091. doi: 10.3389/fcimb.2021.730091

Figure 5.

Figure 5

Status of IVCHT and PHT in patients with B-CS: (A) Heat map of different levels (phyla, genus and species) between IVCHT-PHT-patients and other patients in B-CS independent of treatment. (B) Heat map of different levels (phyla, genus and species) between IVCHT+PHT+ patients and IVCHT-PHT+/IVCHT+ PHT- patients in B-CS independent of treatment. (C) Distribution of greatest differences in taxa of B-CS vs. healthy controls using LEfSe analysis were presented according to the LDA scores (log10) > 2.0. (D) Evolutionary clade of B-CS different intestinal microbiota, as determined using the LEfSe method. (E) Altered microbial functions in KEGG pathway between IVCHT+PHT+ and IVCHT+PHT-/IVCHT-PHT+, IVCHT-PHT- patients and other B-CS syndrome (IVCHT-PHT+, IVCHT+PHT- and IVCHT+PHT+ patients). B-CS, Budd-Chiari syndrome; PHT, portal hypertension; IVCHT, inferior vena caval hypertension; LDA, linear discriminant analysis; KEGG, Kyoto Encyclopaedia of Genes and Genomes; LEfSe, linear discriminant analysis effective size. *P < 0.05, **P < 0.01.