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. 2021 Nov 1;10(1):2010–2015. doi: 10.1080/22221751.2021.1994356

Table 1.

Summary of main details for the 4 Delta sublineages reported in the current survey.

sublineage case (gender/age) GISAID entry extra mutation in S protein overall frequency as of September 21, 2021 frequency in Delta sublineage as of September 21, 2021
#1 F/26 M/65 EPI_ISL_3232432 EPI_ISL_3232507 S71F 2,003 sequences, the highest frequency (2%) occurring in the B.1.605 strain from the USA

  • B.1.617.2: 102 out of 522,766

  • AY.5: 25 out of 28,097

  • AY.7.2: 1 out of 2,002

  • AY.4: 110 out of 390,000

  • AY.3: 6 out of 33,823

  • AY.20: 2 out of 12,423

  • AY.1: 1 out of 12,423

  • AY.6: 1 out of 12,109

  • AY.25: 4 out of 53,493

  • AY.9: 2 out of 30,948

  • AY.12: 3 out of 49,152
T250I 6,194 sequences, the highest frequency (1%) occurring in B.1.617.2

  • B.1.617.2: 4,862 out of 522,766

  • AY.11: 6 out of 984

  • AY.10: 32 out of 7,165

  • AY.21: 4 out of 952

  • < 0.5% in AY.7.1, AY.25, AY.22, AY.19, AY.12, AY.4, AY.13, AY.24, AY.5, AY.7.2, AY.23, AY.1, AY.20, AY.14, AY.3, AY.6, AY.9
T572I 12,017 sequences, being a hallmark mutation of the uncommon B.1.177.88 and B.1.1486 lineages, and partly of the B.1.284 lineage

  • B.1.617.2: 2,058 out of 522,766

  • AY.16: 30 out of 1,629

  • AY.5.1: 2 out of 233

  • < 0.5% in AY.7.2, AY.7.1, AY.4, AY.12, AY.25, AY.21, AY.10, AY.23, AY.15, AY.7, AY.24, AY.13, AY.3, AY.5, AY.20, AY.2, AY.3.1, AY.9, AY.6
K854N 2,768 sequences, being the hallmark mutation of the uncommon B.1.1.384 lineage, and partly of the B.1.623 lineage from the USA

  • B.1.617.2: 348 out of 522,766

  • AY.22: 20 out of 433

  • AY.4: 1,054 out of 390,000

  • AY.10: 10 out of 7,165

  • AY.15: 3 out of 2,868A

  • AY.19: 1 out of 1,335

  • AY.7.2: 1 out of 2,002

  • AY.9: 15 out of 30,948

  • AY.13: 1 out of 2,956

  • <0.5% in AY.14, AY.12, AY.5, AY.25, AY.6, AY.20
#2 F/44 EPI_ISL_3232508 G769V 15,725 sequences, being the hallmark mutation of lineages B.1.1.91, R.1, B.1.177.78, B.1.1.123, and B.1.1.421

  • AY.1: 3 out of 1237

  • AY.24: 8 out of 4,350

  • AY.19: 2 out of 1,235

  • AY.16: 2 out of 1,629

  • AY.4: 235 out of 390,000

  • B.1.617.2: 297 out of 522,766

  • < 0.5% in AY.9, AY.7.1, AY.12, AY.3, AY.10, AY.5, AY.6, AY.3.1, AY.7, AY.23, AY.25, AY.20, AY.14
      C1248F 989 sequences, with the highest (5%) prevalence in B.1.264.1 lineage

  • AY.21: 2 out of 952

  • AY.20: 21 out of 12,423

  • AY.1: 1 out of 1,237

  • AY.4: 275 out of 390,000

  • AY.24: 3 out of 4530

  • B.1.617.2: 272 out of 522,766

  • < 0.5% in AY.12, AY.23, AY.7, AY.7.1, AY.10, AY.3, AY.25, AY.5
#3 M/23 EPI_ISL_3239899 A352S 989 sequences, being the hallmark mutation of lineage AH.3 (98% prevalence)

  • B.1.617.2: 43 out of 522,766

  • AY.19: 1 out of 1,335

  • AY.14: 4 out of 6,467

  • AY.15: 1 out of 2,868

  • AY.10: 2 out of 7,165

  • AY.4: 95 out of 390,000

  • AY.6: 2 out of 12,109

  • AY.23: 1 out of 9,258

  • AY.20: 1 out of 12,423

  • AY.3: 2 out of 33,823

  • AY.12: 1 out of 49,152

  • AY.25: 1 out of 53,493
#4 M/45 EPI_ISL_3239897 R158G 1,154 sequences

  • AY.3.1: 116 out of 4,161

  • AY.25: 326 out of 53,493

  • AY.13: 10 out of 2,956

  • AY.22: 1 out of 433

  • AY.3: 59 out of 33,823

  • AY.1: 2 out of 1,237

  • AY.2: 3 out of 2,157

  • AY.10: 9 out of 7,165

  • B.1.617.2: 218 out of 522,766

  • < 0.5% in AY.23, AY.4, AY.8, AY.14, AY.16, AY.5, AY.12, AY.71, AY.9
C1248F 989 sequences

  • B.1.617.2: 272 out of 522,766

  • AY.21: 2 out of 952

  • AY.20: 21 out of 12,423

  • AY.1: 1 out of 1,237

  • < 0.5 in AY.4, AY.24, AY.12, AY.23, AY.7, AY.7.1, AY.10, AY.3, AY.25, AY.5