Table 1:
Year of diagnosis | No. of adults with first KC | No. of deaths from KC | Crude incidence rate per 100 000 (95% CI) | Standardized incidence rate per 100 000 (95% CI)* | Crude mortality rate per 1 000 000 (95% CI) | Standardized mortality rate per 1 000 000 (95% CI)* |
---|---|---|---|---|---|---|
1998 | 29 320 | 57 | 328.6 (324.9–332.4) | 306.2 (302.7–309.7) | 6.39 (4.84–8.28) | 5.79 (4.38–7.50) |
1999 | 28 811 | 74 | 317.3 (313.7–321.0) | 293.4 (290.0–296.9) | 8.15 (6.40–10.23) | 7.39 (5.80–9.30) |
2000 | 28 261 | 75 | 305.2 (301.7–308.8) | 279.7 (276.4–283.0) | 8.10 (6.37–10.15) | 7.13 (5.60–8.95) |
2001 | 28 783 | 73 | 304.2 (300.7–307.7) | 276.5 (273.3–279.8) | 7.71 (6.05–9.70) | 6.63 (5.19–8.35) |
2002 | 27 453 | 85 | 285.5 (282.2–288.9) | 257.3 (254.2–260.3) | 8.84 (7.06–10.93) | 7.39 (5.89–9.15) |
2003 | 26 765 | 149 | 274.2 (271.0–277.5) | 244.7 (241.8–247.7) | 15.27 (12.91–17.92) | 12.34 (10.43–14.51) |
2004 | 27 462 | 160 | 277.4 (274.2–280.7) | 245.2 (242.3–248.2) | 16.16 (13.76–18.87) | 12.85 (10.92–15.03) |
2005 | 28 669 | 145 | 285.8 (282.5–289.1) | 250.0 (247.1–253.0) | 14.45 (12.2–17.01) | 11.06 (9.32–13.04) |
2006 | 29 972 | 150 | 296.6 (293.3–300.0) | 255.8 (252.9–258.8) | 14.85 (12.57–17.42) | 10.99 (9.28–12.93) |
2007 | 29 646 | 194 | 291.2 (287.9–294.5) | 247.6 (244.7–250.5) | 19.05 (16.47–21.93) | 13.93 (12.01–16.06) |
2008 | 31 109 | 204 | 301.5 (298.2–304.9) | 254.1 (251.2–257.0) | 19.77 (17.15–22.68) | 14.24 (12.32–16.39) |
2009 | 31 890 | 250 | 304.3 (300.9–307.6) | 253.9 (251.1–256.8) | 23.85 (20.99–27) | 16.66 (14.62–18.9) |
2010 | 32 980 | 279 | 310.4 (307.1–313.8) | 255.6 (252.7–258.4) | 26.26 (23.27–29.53) | 18.29 (16.15–20.64) |
2011 | 35 209 | 250 | 326.4 (323.0–329.8) | 266.5 (263.6–269.3) | 23.17 (20.39–26.23) | 15.61 (13.68–17.73) |
2012 | 35 217 | 286 | 322.0 (318.6–325.4) | 259.4 (256.6–262.2) | 26.15 (23.21–29.36) | 17.34 (15.32–19.54) |
2013 | 37 051 | 306 | 334.3 (330.9–337.7) | 266.2 (263.4–269) | 27.61 (24.60–30.88) | 17.33 (15.39–19.44) |
2014 | 37 572 | 312 | 335.9 (332.6–339.4) | 263.5 (260.7–266.2) | 27.90 (24.89–31.17) | 17.22 (15.30–19.32) |
2015 | 38 593 | 316 | 341.8 (338.4–345.2) | 264.7 (262–267.4) | 27.98 (24.98–31.25) | 17.02 (15.13–19.09) |
2016 | 40 475 | 358 | 353.9 (350.5–357.4) | 271.2 (268.5–273.9) | 31.31 (28.15–34.72) | 18.65 (16.69–20.77) |
2017 | 41 242 | 353 | 356.7 (353.2–360.1) | 271.0 (268.3–273.7) | 30.53 (27.43–33.89) | 17.22 (15.40–19.19) |
Note: CI = confidence interval.
Age–and sex–standardized using the 1991 Canadian population.