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. 2021 Oct 21;12:750193. doi: 10.3389/fphar.2021.750193

TABLE 6.

Odds ratio (OR) of strong opioids use by sex, age, composite socioeconomic index (quartiles), and cancer diagnosis adjusted for age in Catalonia, 2019.

Cancer No cancer
Men Women Men Women
OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value
0–14 years old a nc nc Nc nc nc nc nc nc nc nc nc nc
15–44 years old
 Q1 (least deprived) 1.00 1.00 1.00 1.00
 Q2 9.41 (4.63–19.12) <0.001 b 1.15 (0.71–1.86) 0.5820 1.92 (1.48–2.50) <0.001 b 1.18 (0.95–1.47) 0.1298
 Q3 8.33 (4.06–17.09) <0.001 b 1.33 (0.82–2.15) 0.2432 1.94 (1.49–2.53) <0.001 b 1.54 (1.25–1.90) <0.001 b
 Q4 (most deprived) 3.43 (1.59–7.43) 0.0018 b 1.76 (1.13–2.73) 0.0126 b 2.27 (1.76–2.92) <0.001 b 1.46 (1.18–1.80) 0.0004 b
45–64 years old
 Q1 (least deprived) 1.00 1.00 1.00 1.00
 Q2 1.05 (0.88–1.26) 0.5633 1.01 (0.84–1.22) 0.8849 1.42 (1.26–1.60) <0.001 b 1.57 (1.43–1.72) <0.001 b
 Q3 1.07 (0.89–1.28) 0.4853 1.02 (0.84–1.24) 0.8102 1.66 (1.48–1.87) <0.001 b 1.96 (1.79–2.15) <0.001 b
 Q4 (most deprived) 1,29 (1.08–1.53) 0.0043 b 1.46 (1.22–1.74) <0.001 a 1.75 (1.56–1.96) <0.001 b 2.24 (2.05–2.45) <0.001 b
65–74 years old
 Q1 (least deprived) 1.00 1.00 1.00 1.00
 Q2 1.17 (0.94–1.46) 0,1601 1.17 (0.92–1.49) 0.1958 1.54 (1.32–1.80) <0.001 b 1.63 (1.49–1.78) <0.001 b
 Q3 1.65 (1.34–2.03) <0.001 b 1.44 (1.14–1.83) 0.0021 b 1.65 (1.41–1.93) <0.001 b 1.71 (1.57–1.88) <0.001 b
 Q4 (most deprived) 1.40 (1.13–1.74) 0.0021 b 1.43 (1.13–1.81) 0.0025 b 1.65 (1.41–1.93) <0.001 b 1.93 (1.76–2.11) <0.001 b
≥75 years old
 Q1 (least deprived) 1.00 1.00 1.00 1.00
 Q2 1.03 (0.82–1.29) 0.8156 0.94 (0.78–1.14) 0.5306 1.23 (1.10–1.38) 0.0003 b 1.27 (1.21–1.33) <0.001 b
 Q3 1.25 (1.00–1.56) 0.0545 0.93 (0.76–1.14) 0.4753 1.28 (1.14–1.44) <0.001 b 1.29 (1.23–1.36) <0.001 b
 Q4 (most deprived) 1.38 (1.11–1.72) 0.0033 b 1.01 (0.83–1.22) 0.9347 1.32 (1.18–1.48) <0.001 b 1.35 (1.28–1.41) <0.001 b
a

The results for the 0–14 age group are not conclusive, due to the low use in this group.

b

Statistical significance at ≤0.05%.