Table 1. Characteristics of the study population (n = 725).
| Variables* | Value | |
|---|---|---|
| Age (years) | 63.4 ± 12.3 | |
| Male gender (%) | 242 (33) | |
| NYHA Functional class† | I/II | 459 (63) |
| III/IV | 252 (35) | |
| Syncope‡ | 78 (11) | |
| Palpitations | 264 (36) | |
| Dyslipidemia | 151 (21) | |
| Diabetes mellitus | 90 (12) | |
| Arterial hypertension | 253 (35) | |
| Chronic kidney disease | 66 (9) | |
| Megaesophagus§ | 77 (11) | |
| Megacolon§ | 46 (6) | |
| NT-ProBNP (pg/mL) | 144 [64/349] | |
| Medications | ||
| Benznidazole treatmentǁ | 174 (24) | |
| ACE inhibitors/ Angiotensin receptor blockers | 420 (58) | |
| Beta blockers (carvedilol) | 138 (19) | |
| Amiodarone | 167 (23) | |
| ECG findings | ||
| Heart rate (bpm) | 66 ± 13.3 | |
| Atrial fibrillation | 32 (4.4) | |
| QTc interval (ms) | 433.4 ± 44.5 | |
| PR interval (ms) | 164.5 ± 35.8 | |
| QRS duration (ms) | 116.6 ± 28.2 | |
| Pacemaker | 22 (3) | |
| RBBB¶ | 224 (31) | |
| LBBB | 24 (3.3) | |
| Ventricular ectopic beats | 15 (2.1) | |
| Low QRS voltage | 40 (5.5) | |
| ST-T abnormalities | 104 (14.3) | |
*Data are expressed as the mean value ± SD, median (interquartile range), or absolute numbers (percentage)
†Functional class was not assessed in 14 patients (2%)
‡reported by the patients
§ radiological exams of the gastrointestinal tract reported by the patients.
ǁPrevious treatment with benznidazole informed by the patients
¶Isolated or associated with left anterior fascicular block (LAFB)
ACE = Angiotensin-converting enzyme inhibitors; LAFB = Left Anterior Fascicular Block, LBBB = Left bundle branch block; NT-ProBNP = N- terminal pro-brain natriuretic peptide; RBBB = Right Bundle Branch Block.