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. 2021 Nov 4;16(11):e0257619. doi: 10.1371/journal.pone.0257619

Table 4. Factors associated with CA-AKI and HA-AKI in hospitalized COVID patients, in the univariable and multivariable logistic regression model.

Univariable analysis, OR (95% CI) p Multivariable analysis, OR (95% CI) p
Community-acquired AKI
Grade COVID
    Mild Reference - Reference -
    Severe 1.15 (1.08–1.21) <0.001 1.08 (1.02–1.14) 0.005
Diabetes 1.18 (1.12–1.25) <0.001 1.08 (1.02–1.15) 0.005
Hypertension 1.22 (1.15–1.29) <0.001 1.07 (1.00–1.14 0.02
CKD 1.56 (1.43–1.70) <0.001 1.47 (1.35–1.60) <0.001
COPD 1.24 (1.06–1.46) 0.007 1.25 (1.07–1.45) 0.003
Serum Leukocytes > 12 [109/L] 1.14 (1.07–1.21) <0.001 1.10 (1.04–1.17) <0.001
Hospital-acquired AKI
COVID severity
    Mild Reference - Reference -
    Severe 1.12 (1.07–1.18) <0.001 1.13 (1.06–1.20) <0.001
Serum Ferritin > 500[ng/m] 1.10 (1.04–1.16) <0.001 1.07 (1.01–1.14) 0.01

AKI, acute kidney injury; CA-AKI, community-acquired AKI; HA-AKI, hospital-acquired AKI; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease.