Table 1. Demographic characteristics and ccf-mtDNA in patients and controls.
| Controls (n = 49) | Current depression (n = 236) | Remitted depression (n = 45) | P-value | |
|---|---|---|---|---|
| Age Mean ± SD | 36.7 ± 13.1 | 38.2 ± 13.5 | 34.0 ± 10.2 | 0.13 |
| Sex N (%) females | 36 (73.5) | 154 (65.3) | 30 (66.7) | 0.54 |
| BMI Mean ± SD | 23.8 ± 4.0 | 26.3 ± 5.3 | 25.3 ± 4.7 | 0.006 |
| Current smokers, N (%) | 3 (6.1) | 48 (20.5) | 12 (26.7) | 0.03 |
| MADRS score (mean, SD) | na | 22.9 ± 7.9 | 14.6 ± 9.1 | <0.001 |
| Current treatment with mood stabilizer N (%) | na | 49 (20.8) | 16 (35.6) | 0.03 |
| Current treatment with antipsychotic N (%) | na | 45 (19.1) | 9 (20.0) | 0.90 |
| Current treatment with antidepressant N (%) | na | 192 (81.7) | 32 (71.1) | 0.20 |
| Ccf-mtDNA (C/μl plasma) (mean, SD) | 105 578 ± 207 848 | 35 683 ± 59 906 | 26 762 ± 26 688 | p<0.001 |
Data was missing for BMI (n = 14), smoking (n = 2) and MADRS (n = 17).