Table 1:
Individuals enrolled in three groups Non-CF, CF-outpatients, and CF-hospitalized.
| Clinical demographics (N=44) | Non-CF (n=15) | CF-outpatient (n=16) | CF-hospitalized (n=13) |
|---|---|---|---|
| Age, years, mean (SD) | 27.4 (6.2) | 39.1 (13.8) | 31.4 (10.9) |
| Male, % (frequency) | 33 (5) | 50 (8) | 54 (7) |
| Most recent FEV1, % predicted, mean (SD) | 51.5 (18.1) | 39.7 (17.3) | |
| Most recent FVC, % predicted, mean (SD) | 66.4 (15.6) | 57.8 (19.9) | |
| Most recent BMI (kg/m2), mean (SD) | 25.5 (5.1) | 19.8 (2.8) | |
| Co-morbidities, % (frequency) | |||
| Pancreatic insufficiency | 93.8 (15) | 100 (13) | |
| CF-related diabetes | 37.5 (6) | 38.5 (5) | |
| Liver disease | 12.5 (2) | 7.7 (1) | |
| Implanted central venous access | 12.5 (2) | 46.2 (6) | |
| Allergic bronchopulmonary aspergillosis | 12.5 (2) | 0 (0) | |
| Autoimmunity | 12.5 (2) | 0 (0) | |
| History of cancer | 18.8 (3) | 7.7 (1) | |
| Genotype, % (frequency) | |||
| F508del/F508del | 25 (4) | 30.8 (4) | |
| F508del/Minimal Function | 62.5 (10) | 38.5 (5) | |
| Gating | 0 (0) | 23.1 (3) | |
| Null/Null | 6.3 (1) | 7.7 (1) | |
| Minimal Function (no F508del) | 6.3 (1) | 0 (0) | |