Appendix Table 2.
Characteristics of BRCA-positive Women and Women with Prior Breast Cancer Enrolled in 2016a
| Subgroup | ||||
|---|---|---|---|---|
| All Women with BRCA Mutation | Women with BRCA Mutation and without Prior Breast Cancer | Women with BRCA Mutation and with Prior Breast Cancer | Women without BRCA Mutation and with Prior Breast Cancer | |
| Characteristics | N(%) | N (%) | N (%) | N (%) |
| Total population | 6,953 | 4,565 | 2,745 | 42,790 |
| Age, years(1%) | ||||
| 20–29 | 413 (6%) | 397 (9%) | 25 (1%) | 87 (<1%) |
| 30–39 | 1,320 (19%) | 1,064 (23%) | 313 (11%) | 1,159 (3%) |
| 40–49 | 2,234 (32%) | 1,405 (31%) | 968 (35%) | 7,721 (18%) |
| 50–64 | 2,986 (43%) | 1,699 (37%) | 1,439 (53%) | 33,823 (79%) |
| Race/ethnicity b | ||||
| White neighborhood | 4,301 (62%) | 2,804 (61%) | 1,703 (62%) | 25,836 (60%) |
| Black neighborhood | 62 (<1%) | 34 (1%) | 30 (1%) | 819 (2%) |
| Mixed neighborhood | 1,460 (21%) | 960 (21%) | 583 (21%) | 9,265 (22%) |
| Hispanic surname | 462 (7%) | 328 (7%) | 157 (6%) | 3,076 (7%) |
| Asian surname | 192 (3%) | 118 (3%) | 86 (3%) | 1,345 (3%) |
| Missing | 476 (7%) | 321 (7%) | 186 (7%) | 2,449 (6%) |
| Region of US | ||||
| West | 1,560 (22%) | 1,045 (23%) | 600 (22%) | 8,886 (21%) |
| South | 2,636 (38%) | 1,731 (38%) | 1,035 (38%) | 17,996 (42%) |
| Midwest | 1,860 (27%) | 1,200 (26%) | 766 (28%) | 11,284 (26%) |
| Northeast | 888 (13%) | 582 (13%) | 342 (12%) | 4,511 (11%) |
| Missing | 9 (<1%) | 7 (<1%) | 2 (<1%) | 113 (<1%) |
| Neighborhood poverty c | ||||
| <10% | 4,048 (58%) | 2,611 (57%) | 1,630 (59%) | 23,266 (55%) |
| ≥10% | 2,365 (34%) | 1,583 (35%) | 909 (33%) | 16,779 (39%) |
| Missing | 540 (8%) | 371 (8%) | 206 (8%) | 2,745 (6%) |
a
Optum’s de-identified Clinformatics® Data Mart Database (Eden Prairie, MN)
b
White and Black neighborhood defined using the 2008–2012 American Community Survey as a census tract with ≥75% of residents being one race; Mixed neighborhoods defined as census tracts with no majority race; Hispanic and Asian defined using surname analysis.
c
Poverty levels defined using the 2008–2012 American Community Survey at the census tract level.