Table 3.
Univariate and multivariate regression analyses of OS in HCC patients of the TCGA training group.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| P | Hazard ratio | 95% confidence interval | P | Hazard ratio | 95% confidence interval | |
| Age (≥60/<60) | 0.220 | 1.378 | 0.826-2.301 | |||
| Sex (female/male) | 0.776 | 1.079 | 0.639-1.822 | |||
| AJCC stage (IV + III/II + I) | 0.007 | 2.061 | 1.216-3.494 | 0.042 | 1.745 | 1.021-2.983 |
| Histologic grade (G4 + G3/G2 + G1) | 0.276 | 0.744 | 0.437-1.266 | |||
| Risk score (high/low) | <0.001 | 4.027 | 2.410-6.728 | <0.001 | 3.775 | 2.251-6.328 |
Notes: AJCC: American Joint Committee on Cancer; OS: overall survival; HCC: hepatocellular carcinoma; TCGA: The Cancer Genome Atlas.