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. 2021 Oct 28;2021:8321400. doi: 10.1155/2021/8321400

Scheme 1.

Scheme 1

General procedure for the synthesis of target compounds 5, 6, and 7a-l. Reagents and conditions: (i) thionyl chloride (SOCl2), dicloroethane, reflux, 2 h; (ii) 4-aminibenzoic acid, triethylamine (TEA), acetonitrile, stirring, rt; (iii) thionyl chloride (SOCl2), dichloroethane, reflux, 2 h; (iv) cyclohexylamine, treithylamine (TEA), acetonitrile, reflux, 2 h; (v) benzylamine, treithylamine (TEA), acetonitrile, reflux, 2 h; (vi) app. amine, treithylamine (TEA), acetonitrile, reflux, 2 h.