Table 3.
Caspase 3 concentrations, BAX and Bcl-2 expression levels, and TNF-α percent inhibition in HepG-2 cells treated with the tested compounds.
| Comp. | Caspase 3 | BAX | Bcl-2 | TNF-α % inhibition |
|||
|---|---|---|---|---|---|---|---|
| Conc. (Pg/ml) | Fold | Conc. (Pg/ml) | Fold | Conc. (Pg/ml) | Fold | ||
| 11c | 271.41 | 5.28 | 133.2 | 6.17 | 2.81 | 0.52 | 31% |
| 11d | 391.23 | 7.61 | 237.9 | 11.02 | 1.72 | 0.32 | 81% |
| 11f | 292.11 | 5.68 | 142.5 | 6.60 | 2.25 | 0.42 | 60% |
| 11g | 324.36 | 6.31 | 160.2 | 7.42 | 2.55 | 0.48 | 47% |
| 10 | 334.57 | 6.51 | 231.6 | 10.73 | 2.72 | 0.51 | 40% |
| 18b | 310.75 | 6.04 | 154.4 | 7.15 | 2.51 | 0.47 | 54% |
| 18a | 267.64 | 5.20 | 113.5 | 5.26 | 2.63 | 0.49 | 45% |
| 7a | 401.15 | 7.80 | 261.4 | 12.11 | 1.25 | 0.23 | 87% |
| 7b | 397.61 | 7.73 | 257.5 | 11.93 | 1.92 | 0.36 | 72% |
| 5 | 345.5 | 6.72 | 232.7 | 10.78 | 1.35 | 0.25 | 85% |
| 7l | 340.42 | 6.62 | 226.9 | 10.51 | 2.11 | 0.39 | 74% |
| Control | 51.38 | 1.00 | 21.57 | 1.00 | 5.31 | 1.00 | 86% |