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. 2021 Oct 28;2021:4877311. doi: 10.1155/2021/4877311

Table 5.

Binary variable meta-analysis results.

Effect index Detail index Study Heterogeneity test Model RR (95% CI)
Adverse reactions Vomiting 3 [16, 22, 27] I 2  = 0%, P=0.90 Fixed effects model 0.83 (0.46, 1.51), P=0.55
Stress ulcer 2 [22, 30] I 2  = 14%, P=0.28 Fixed effects model 0.47 (0.22, 1.02), P=0.06
Esophageal reflux 8 [11, 13, 16, 17, 22, 28, 29, 31] I 2  = 29%, P=0.19 Fixed effects model 0.43 (0.25, 0.74), P=0.002
Bloating 10 [11, 13, 17, 22, 27, 29, 31, 33] I 2  = 0%, P=0.45 Fixed effects model 0.39 (0.26, 0.58), P < 0.00001
Constipation 12 [11, 13, 16, 19, 23, 27, 29, 33] I 2  = 0%, P=0.76 Fixed effects model 0.31 (0.21, 0.45), P < 0.00001
Diarrhea 14 [11, 13, 16, 19, 22, 23, 27, 29, 31] I 2  = 0%, P=0.93 Fixed effects model 0.22 (0.14, 0.34), P < 0.00001
Gastric retention 4 [11, 13, 2729] I 2  = 0%, P=0.84 Fixed effects model 0.34 (0.19, 0.60), P=0.0002
Gastrointestinal bleeding 10 [13, 15, 17, 19, 25, 26, 28, 29, 31] I 2  = 0%, P=0.93 Fixed effects model 0.39 (0.28, 0.54), P < 0.00001

Complication rate Lung infection 12 [11, 13, 15, 17, 25, 26, 2832] I 2  = 65%, P=0.0009 Random effects model 0.44 (0.27, 0.72), P=0.001
Gastrointestinal infection 4 [11, 13, 17, 29] I 2  = 0%, P=0.96 Fixed effects model 0.40 (0.23, 0.68), P=0.0008
Urinary tract infection 6 [11, 13, 15, 17, 28, 29] I 2  = 0%, P=0.93 Fixed effects model 0.27 (0.15, 0.49), P < 0.0001

Poor prognostic indicators Mortality rate 4 [16, 17, 22, 29] I 2  = 0%, P=0.44 Fixed effects model 0.45 (0.22, 0.93), P=0.03
Bacterial imbalance rate 6 [11, 15, 25, 26, 28, 32] I 2  = 0%, P=0.79 Fixed effects model 0.32 (0.21, 0.48), P < 0.0001