Table 2.
Univariate analysis of factors associated to liver disease decompensation
|
Examined parameter, baseline values
|
Patients who remained compensated during follow-up, n = 24
|
Patients who proceed to decompensated disease during follow-up, n = 12
|
P
value
|
| Sex as M/F | 13/11 | 3/9 | 0.157 |
| Age in yr1 | 59 ± 12 | 61 ± 14 | 0.710 |
| Liver-specific treatment, Y/N | 13/11 | 9/3 | 0.292 |
| High-grade varices, Y/N | 6/24 | 6/12 | 0.157 |
| Platelet count as × 109/L | 138 ± 54 | 105 ± 46 | 0.094 |
| Albumin in g/dL | 3.64 ± 0.53 | 4.13 ± 0.51 | 0.013 |
| Spleen diameter in cm | 13.1 ± 2.5 | 14.0 ± 2.3 | 0.325 |
| Portal diameter in cm | 1.29 ± 0.22 | 1.27 ± 0.21 | 0.768 |
| Liver stiffness in kPa | 19.7 ± 6.9 | 23.9 ± 9.2 | 0.139 |
| Spleen stiffness in kPa | 31.1 ± 7.4 | 36.1 ± 9.3 | 0.087 |
| Serum zonulin levels in ng/mL | 3.19 ± 1.02 | 4.15 ± 0.95 | 0.011 |
1
Quantitative variables are expressed as mean±standard deviation.
F: Female; M: Male; N: No; Y: Yes.