Table 1. The effects of nicotinamide mononucleotide (NMN) supplementation during IVM on oocyte quality and embryo development.
NMN (µM) |
Oocytes matured (%) |
Oocytes cleaved (%) |
Blastocyst formation (%) |
Hatching blastocysts (%) |
Total blastocyst cell number |
---|---|---|---|---|---|
Control | 72.2 ± 9.5 | 92.9 ± 3.2 | 23.0 ± 10.0 | 15.8 ± 11.8 | 78.0 ± 7.3 |
0.1 | 76.5 ± 7.0 | 89.9 ± 2.9 | 29.8 ± 9.0 | 20.1 ± 7.4 | 65.5 ± 6.1 |
1 | 77.2 ± 5.1 | 89.8 ± 2.4 | 23.3 ± 6.1 | 30.7 ± 2.4 | 71.6 ± 6.9 |
10 | 78.0 ± 3.6 | 91.5 ± 3.0 | 28.2 ± 5.4 | 15.8 ± 3.4 | 79.3 ± 7.0 |
100 | 68.5 ± 8.6 | 89.7 ± 5.3 | 22.1 ± 4.6 | 25.4 ± 4.6 | 75.1 ± 10.3 |
Data presented as mean ± SEM.