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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Int J Drug Policy. 2021 Jul 8;96:103354. doi: 10.1016/j.drugpo.2021.103354

Table 4.

Association of individual drug use stigma items with hepatitis C virus (HCV) infection.

Drug use stigma items Outcome: HCV RNA positive (weighted)
Univariable OR (95% CI) a Multivariable Model 1: aOR (95% CI) a,b Multivariable Model 2: aOR (95% CI) a,c

Enacted stigma items
(Ref: never)

1. Mistreated by hospital worker 1.20 (1.03–1.41) 1.19 (1.00–1.40) 1.17 (1.01–1.35)
2. Denied medical care or hospital services 1.21 (1.01–1.44) 1.21 (1.01–1.45) 1.21 (0.99–1.49)
3. Told to stay away from children 1.24 (1.02–1.50) 1.32 (1.15–1.51) 1.25 (1.07–1.45)
4. Forced to move out of home by family 1.14 (0.98–1.34) 1.21 (1.05–1.39) 1.16 (1.01–1.33)
5. Received threat of physical harm 1.22 (1.06–1.40) 1.24 (1.12–1.38) 1.17 (1.06–1.30)
6. Denied housing 1.23 (1.04–1.47) 1.27 (1.09–1.49) 1.26 (1.08–1.46)

Vicarious stigma items
(Ref: never)

7. Mistreated by hospital workers 1.17 (0.96–1.44) 1.19 (1.00–1.41) 1.15 (0.96–1.38)
8. Mistreated when getting HIV testing 1.18 (0.95–1.47) 1.17 (0.96–1.43) 1.19 (0.95–1.48)
9. Mistreated when getting HIV treatment 1.16 (0.97–1.40) 1.17 (0.97–1.40) 1.17 (0.95–1.43)
10. Refused care from family when sick 1.08 (0.83–1.40) 1.13 (0.92–1.37) 1.07 (0.86–1.33)
11. Forced to move out of home by family 1.05 (0.84–1.30) 1.07 (0.91–1.26) 1.02 (0.85–1.22)
12. Ostracized by community or village 1.12 (0.97–1.30) 1.12 (0.97–1.28) 1.07 (0.92–1.25)

Felt normative stigma items
(Ref: no one/very few people)

13. Avoid visiting homes of PWUD 1.01 (0.87–1.17) 0.99 (0.84–1.17) 0.97 (0.82–1.15)
14. PWUD bring shame to their families 1.04 (0.87–1.24) 1.00 (0.83–1.21) 0.96 (0.81–1.15)
15. PWUD should feel guilty 1.06 (0.92–1.21) 1.03 (0.91–1.16) 1.00 (0.88–1.13)
16. PWUD are disgusting 1.01 (0.87–1.18) 0.99 (0.85–1.15) 0.96 (0.83–1.12)
17. PWUD are paying for their karma or sins 1.04 (0.89–1.22) 1.00 (0.85–1.17) 0.98 (0.84–1.16)

Internalized stigma items
(Ref: not at all/a little)

18. Feels need to avoid visiting people due to drug use 1.29 (1.12–1.49) 1.25 (1.06–1.48) 1.19 (1.01–1.40)
19. Feels shame brought to family due to drug use 1.45 (1.24–1.70) 1.40 (1.20–1.63) 1.32 (1.14–1.54)
20. Feels guilty about drug use 1.31 (1.04–1.67) 1.29 (1.02–1.64) 1.24 (0.99–1.55)
21. Feels disgusting about drug use 1.29 (1.06–1.57) 1.24 (1.03–1.49) 1.19 (1.01–1.41)
22. Uses drugs as a payment for karma or sins 1.24 (1.02–1.49) 1.22 (1.02–1.46) 1.19 (1.00–1.42)
a

Separately for each stigma item, odds ratios (OR) of active hepatitis C virus infection were estimated from multilevel logistic regression models with a random-intercept for each site and scaled RDS-II weights.

b

Multivariable model 1 included adjustment for age group, gender, northeast region, educational attainment, experiencing homelessness, history of incarceration in the past 6 months, alcohol use/dependence (AUDIT), and HIV status.

c

Multivariable model 2 included adjustment for age group, gender, northeast region, educational attainment, experiencing homelessness, history of incarceration in the past 6 months, alcohol use/dependence (AUDIT), HIV status, frequency of injection in the past 6 months and a history of ever sharing needles/syringes.