Table 4.
Measure | Total Hippocampal Volume | 18F-Flutemetamol SUVR | ||||
---|---|---|---|---|---|---|
r | r2 | p value | r | r2 | p value | |
HVLT-R LR | .39 | .15 | <.001 | −.35 | .12 | <.001 |
BVMT-R LR | .37 | .14 | <.001 | −.48 | .23 | <.001 |
Aggregate HVLT-R/BVMT-R LR | .45 | .20 | <.001 | −.49 | .24 | <.001 |
RBANS List Learning LR | .40 | .16 | <.001 | −.44 | .19 | <.001 |
RBANS Story Memory LR | .41 | .17 | <.001 | −.50 | .25 | <.001 |
Aggregate RBANS LR | .46 | .21 | <.001 | −.53 | .28 | <.001 |
HVLT-R RLS | .27 | .07 | .006 | −.01 | .01 | .92 |
BVMT-R RLS | .24 | .06 | .01 | −.31 | .10 | .001 |
Aggregate HVLT-R/BVMT-R RLS | .33 | .11 | <.001 | −.22 | .05 | .03 |
RBANS List Learning RLS | .31 | .10 | .001 | −.27 | .07 | .005 |
RBANS Story Memory RLS | .21 | .04 | .06 | −.18 | .03 | .06 |
Aggregate RBANS RLS | .32 | .10 | .001 | −.28 | .08 | .003 |
HVLT-R Trial One | .32 | .10 | .001 | −.59 | .35 | <.001 |
BVMT-R Trial One | .35 | .12 | <.001 | −.47 | .22 | <.001 |
RBANS List Learning Trial One | .25 | .06 | .008 | −.44 | .19 | <.001 |
RBANS Story Memory Trial One | .28 | .08 | .004 | −.53 | .28 | <.001 |
HVLT-R Total Recall | .42 | .18 | <.001 | −.61 | .37 | <.001 |
BVMT-R Total Recall | .42 | .17 | <.001 | −.58 | .34 | <.001 |
RBANS List Learning Total Score | .38 | .15 | <.001 | −.57 | .32 | <.001 |
RBANS Story Memory Total Score | .36 | .13 | <.001 | −.62 | .38 | <.001 |
Note: HVLT-R = Hopkins Verbal Learning Test – Revised, LR = Learning Ratio, BVMT-R = Brief Visual Memory Test – Revised, RBANS = Repeatable Battery for the Assessment of Neuropsychological Status, and RLS = Raw Learning Score. Significance values reflect p value relationship between learning score and either total hippocampal volume or 18F-Flutemetamol composite SUVR uptake. Effect Sizes were measured using r2 values. A two-tailed alpha level was set at .01 for all analyses. The total hippocampal volume variable was additionally adjusted for total intracranial volume.