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. 2021 Nov 4;11:21690. doi: 10.1038/s41598-021-00699-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Overall profile of bacterial composition in ileal mucous membrane. (a) The bacterial OTU in ileal mucous membrane (Venn figures). The number in the color circus or overlapped circus represented the owned OTU in one or more groups and correlated proportion. (b) Bacterial composition at the phylum level. (c) Bacterial composition at the phylum genus level. *in the same column means P < 0.05, **P < 0.01, and ***P < 0.001. (d,e) PCoA analysis of UniFrac distance metric of bacterial OTUs at the genus level (d) and phylum level (e). Figure was drawn by the ANOSIM of UniFrac distance metric. (f,g) One-way ANOVA analysis of bacterial composition at the phylum level (f) and phylum genus level (g). * n the same column means P < 0.05, **P < 0.01, and ***P < 0.001. The Microsoft Office Excel 2010 was used to as the stamp software.

Overall profile of bacterial composition in ileal mucous membrane. (a) The bacterial OTU in ileal mucous membrane (Venn figures). The number in the color circus or overlapped circus represented the owned OTU in one or more groups and correlated proportion. (b) Bacterial composition at the phylum level. (c) Bacterial composition at the phylum genus level. *in the same column means P < 0.05, **P < 0.01, and ***P < 0.001. (d,e) PCoA analysis of UniFrac distance metric of bacterial OTUs at the genus level (d) and phylum level (e). Figure was drawn by the ANOSIM of UniFrac distance metric. (f,g) One-way ANOVA analysis of bacterial composition at the phylum level (f) and phylum genus level (g). * n the same column means P < 0.05, **P < 0.01, and ***P < 0.001. The Microsoft Office Excel 2010 was used to as the stamp software.