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. 2021 Oct 11;53(10):1569–1579. doi: 10.1038/s12276-021-00684-x

Fig. 5. Prmt1 inhibition in VSMCs elevates cellular stress triggered by mechanical stretch.

Fig. 5

a Immunoblot analysis of γH2AX in the f/f and smKO aortas. b Quantification of the γH2AX intensity relative to β-actin. (n = 5). Data represent the mean ± SD. *P < 0.05, Student’s t-test. c Immunostaining for γH2AX in A7R5 cells treated with Fura followed by 10% cyclic stretch for 2 h. Scale bar: 50 μm. d Quantification of γH2AX-positive cells (red) (n = 89–114). Data represent the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, Student’s t-test.