Table 4.
Effect of 4-HI on inflammatory cytokines levels in rats treated with ICH.
| S. No. | Groups |
Inflammatory markers (pg/mg protein) |
||
|---|---|---|---|---|
| TNF-α | IL-1β | IL-17 | ||
| 1. | Vehicle control | 105.8 ± 0.36 | 78.97 ± 0.41 | 41.91 ± 0.31 |
| F2. | Sham control | 103.8 ± 0.33 | 76.99 ± 0.42 | 40.43 ± 0.42 |
| 3. | 4-HI 100 Per se | 104.7 ± 0.41 | 77.97 ± 0.41 | 41.06 ± 0.35 |
| 4. | ALB | 309.4 ± 0.23* | 583.4 ± 0.33* | 650.9 ± 0.20* |
| 5. | ALB + 4-HI 50 | 269.8 ± 0.35@ | 484.7 ± 0.41@ | 451.1 ± 0.28@ |
| 6. | ALB + 4-HI 100 | 253.2 ± 0.41@# | 435.8 ± 0.82@# | 251.5 ± 0.32@# |
One-way ANOVA followed by (post-hoc Tukey’s test) was used
*
p < 0.001 v/s vehicle group; sham and 4-HI 100 Per se;
@
p < 0.001 v/s ALB;
@#
p < 0.001 v/s ALB + 4-HI 50 (n = 6).