Table 5a.
Effect of 4-HI on oxidative stress markers levels in rats treated with ICH.
| S. No. | Groups |
Oxidative stress markers |
|||
|---|---|---|---|---|---|
|
AchE (µM/mg protein) |
SOD (µM/mg protein) |
GSH (µM/mg protein) |
LDH (U/L) |
||
| 1. | Vehicle control | 13.79 ± 0.37 | 96.98 ± 0.47 | 22.34 ± 0.29 | 411.3 ± 0.62 |
| 2. | Sham control | 13.14 ± 0.45 | 97.13 ± 0.54 | 22.29 ± 0.28 | 409.5 ± 0.61 |
| 3. | 4-HI 100 Per se | 13.56 ± 0.26 | 97.92 ± 0.46 | 22.66 ± 0.45 | 410.4 ± 0.59 |
| 4. | ALB | 50.36 ± 0.44* | 30.54 ± 1.73* | 6.17 ± 0.20* | 1018 ± 36.29* |
| 5. | ALB + 4-HI 50 | 32.85 ± 0.47# | 59.73 ± 0.57# | 8.91 ± 0.19# | 805.2 ± 13.23# |
| 6. | ALB + 4-HI 100 | 25.15 ± 0.43#@ | 70.86 ± 0.33#@ | 12.04 ± 0.19#@ | 657.1 ± 11.22#@ |
One-way ANOVA followed by (post-hoc Tukey’s test) was used. *p < 0.01 v/s vehicle control; sham control and 4-HI 100 Per se; @p < 0.01 v/s ALB; @#p < 0.01 v/s ALB + 4-HI 50; (n = 6).