Fig. 9.

Immunohistochemical photos of rat kidney showing the effect of polycystic ovary syndrome (PCOS), chamomile flower extract, and metformin (Met) treatments on kidney apoptosis gene Bcl2. Control photos show marked Bcl2 gene expression in the kidney cortex and weak Bcl2 gene expression in the medulla. PCOS photos show weak Bcl2 staining in cortical glomerular capillaries (white arrow), medulla loops of Henle (dotted black arrows), and other tubules (black arrows). Chamomile photos show a marked increase in Bcl2 gene expression in both cortex and medulla. Metformin (Met) photos show weak Bcl2 gene expression in the cortex and moderate Bcl2 gene expression in the medulla.