TABLE 2.

Cefazolin MIC distribution among M. tuberculosis clinical isolates. Isoniazid and rifampin were used at a single drug concentration to reconfirm the drug-susceptible or MDR-TB status. Cefazolin MIC₅₀ (in combination with avibactam) for the clinical isolates was 2 mg/L, whereas MIC₉₀ was calculated as 8 mg/L.

Clinical strain	Rifampin (1 mg/L)	Isoniazid (0.1 mg/L)	Cefazolin [with 15 mg/L avibactam]
1A	S	S	2
3A	S	S	2
6B	S	S	4
7A	S	S	2
8A	S	S	8
10B	S	S	2
18B	S	S	4
3D3	R	R	4
6C	R	R	8
7C4	R	R	2
9C	R	R	2
11D1	R	R	2
12D4	R	R	8
16D	R	R	2
18D3	R	R	2
20D2	R	R	2
14C3	R	R	2

S, sensitive; R, resistant.