Table 1.
Characteristics of patients included in the derivation and validation set.
| Derivation set (n = 297) | Validation set (n = 160) | |
|---|---|---|
| Age,† mean (SD) | 65.6 (15.3) | 68.9 (13.2) |
| Sex (female), n (%) | 143 (48.1%) | 82 (51.2%) |
| Hypertension,‡ n (%) | 198 (66.7%) | 126 (78.8%) |
| Diabetes mellitus, n (%) | 64 (21.5%) | 43 (26.9%) |
| History of stroke or TIA, §n (%) | 43 (14.5%) | 20 (12.5%) |
| History of atrial fibrillation, n (%) | 97 (32.7%) | 53 (33.1%) |
| Hemorrhagic transformation|| | ||
| None, n (%) | 121 (40.7%) | 83 (51.9%) |
| Hemorrhage infarction type 1 (HI1), n (%) | 58 (19.5%) | 34 (21.2%) |
| Hemorrhage infarction type 2 (HI2), n (%) | 51 (17.2%) | 27 (16.9%) |
| Parenchymal hematoma type 1 (PH1), n (%) | 43 (14.5%) | 8 (5.0%) |
| Parenchymal hematoma type 2 (PH2), n (%) | 23 (7.7%) | 8 (5.0%) |
| NIHSS score at discharge, ¶ median (IQR) | 6 (2–14) | 8 (3–16) |
| Infarct volume at early follow up, ** median (IQR) | 26.2 (10.6–67.5) | 37.7 (22.5–89.9) |
| Premorbid mRS, median (IQR) | 0 (0–0) | 0 (0–0) |
†
p = 0.02;
‡
p = 0.01;
§
missing value: derivation set (n = 1);
||
p = 0.01, graded per European cooperative acute stroke study criteria, missing value: derivation set (n = 1);
¶
p = 0.03;
**
missing values: derivation set (n = 44), p < 0.001.
Wilcoxon rank-sum test for age; Fisher's exact test for sex, hypertension, history of stroke or TIA, history of smoking, and history of atrial fibrillation.