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. 2021 Oct 18;53(10):1451–1458. doi: 10.1038/s12276-021-00606-x

Table 1.

Overview of existing human intestinal organoid biobanks.

Organ of origin Disease Number of lines Molecular/phenotypic profiling analysis Academic/ Commercial References
Colorectum Colorectal carcinoma 22 Whole-exome sequencing, gene expression Academic 28
Colorectum Colorectal carcinoma 55 Whole-exome sequencing, gene expression, immunohistochemistry Academic 29
Pancreas Pancreatic ductal adenocarcinomas 39 Whole-exome sequencing, methylation, gene expression, immunohistochemistry and in situ hybridization Academic 33
Pancreas Pancreatic ductal adenocarcinomas 114 Whole-genome sequencing, whole-exome sequencing, gene expression Academic 34
Colorectum and esophagus Colorectal and gastroesophageal cancer Not specified Whole-genome sequencing, gene expression, immunohistochemistry, CISH, and FISH Academic 9
Stomach Gastric cancer 63 Whole-genome sequencing, gene expression, CISH, gene set enrichment analysis Academic 35
Intestine Cystic fibrosis 664 Whole-genome sequencing Academic 36
Pancreas Pancreatic cancer 30 Whole-genome sequencing, gene expression, immunohistochemistry Academic 37
Stomach Gastric cancer 20 Whole-genome sequencing, gene expression Academic 38
Intestine, lungs, colorectum, head, neck, liver, ovary Normal, cancer, genetic diseases >1000 Not specified Commercial https://huborganoids.nl/
Intestine, brain, lungs, muscle, breast, kidney, skin Cancer Not specified Not specified Commercial www.attc.org
Colorectum Cancer Not specified Whole-genome sequencing Commercial (https://cellesce.com)
Intestine iPSC-derived intestinal organoids Not specified Gene expression Commercial https://www.definigen.com/products/intestinal/organoid/
Retina, gut, brain, pancreas, Inner ear, liver Stem cells derived organoids Not specified Not specified Commercial https://sunbioscience.ch/
Colon iPSC-derived colon organoids Not specified Gene expression analysis of colon markers, genotyping by STR analysis Commercial https://www.sigmaaldrich.com/