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. 2021 Oct 27;53(10):1636–1646. doi: 10.1038/s12276-021-00686-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a The percentage of Bifidobacterium spp. fluctuated with age but was significantly reduced in Pre-BC compared with Pre-C, whereas Anaerostipes and Bacteroides fragilis were specifically increased in Pre-BC. b The percentages of Akkermansia muciniphila and Phascolarctobacterium fluctuated with age but were significantly reduced in Post-BC compared with Post-C, whereas Proteobacteria and Klebsiella pneumoniae were specifically increased in Post-BC. c The percentages of Faecalibacterium prausnitzii, Ruminococcus gnavus, and Rothia mucilaginosa were simultaneously reduced in Pre-BC, and Post-BC, while Sutterella, and Haemophilus parainfluenzae were simultaneously increased in Pre-BC and Post-BC.