Table 3.
Cut-off value | Sensitivity (%) | Specificity (%) | AUC (95% CI) | P value | |
---|---|---|---|---|---|
CA125 (U/mL) at primary diagnosis | 46.50 | 36.1 | 81.1 | 0.578 (0.469, 0.686) | 0.158 |
HE4 (pmol/L) at primary diagnosis | 89.50 | 61.1 | 72.1 | 0.669 (0.569, 0.769) | 0.002 |
CA125 (U/mL) at recurrence | 32.45 | 71.0 | 93.4 | 0.822 (0.714, 0.930) | < 0.001 |
HE4 (pmol/L) at recurrence | 92.50 | 61.3 | 96.2 | 0.850 (0.765, 0.935) | < 0.001 |
Both CA125 and HE4 at recurrence | 80.6 | 91.5 | 0.900 (0.825, 0.974) | < 0.001 |
CI confidence interval.