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. 2021 Nov 4;11:21694. doi: 10.1038/s41598-021-01263-w

Table 3.

Prediction performance of type II EC recurrence assessment by serum CA125 and HE4.

Cut-off value Sensitivity (%) Specificity (%) AUC (95% CI) P value
CA125 (U/mL) at primary diagnosis 46.50 36.1 81.1 0.578 (0.469, 0.686) 0.158
HE4 (pmol/L) at primary diagnosis 89.50 61.1 72.1 0.669 (0.569, 0.769) 0.002
CA125 (U/mL) at recurrence 32.45 71.0 93.4 0.822 (0.714, 0.930) < 0.001
HE4 (pmol/L) at recurrence 92.50 61.3 96.2 0.850 (0.765, 0.935) < 0.001
Both CA125 and HE4 at recurrence 80.6 91.5 0.900 (0.825, 0.974) < 0.001

CI confidence interval.