Table 8.

Physicochemical properties of all the predicted epitopes within the RBD of S protein

Type of epitopes	Peptide sequence	Antigenicity Score	Mutation	H ydroph-obicity	Charge	Molecular weight	Non- digesting enzymes
B-cell epitopes	YGFQPT	1.0190	No Mutation	− 0.02	0.00	711.85	Trypsin, Clostripain, Cyanogen Bromide, IodosoBenzoate, Staph Protease, Trypsin K, Trypsin R, AspN, Elastase
	YKLPDDFT	1.0171	No Mutation	− 0.20	− 1.00	998.20	Clostripain, Cyanogen Bromide, IodosoBenzoate, Staph Protease, Trypsin R, Elastase
	LFRKSNLKP	1.0196	No Mutation	− 0.36	3.00	1102.47	Cyanogen Bromide, IodosoBenzoate, Proline endopept, Staph Protease, AspN
Cytotoxic T-cell epitopes	NATRFASVY	1.03	No Mutation	− 0.13	1.0	1028.24	Cyanogen Bromide, IodosoBenzoate, Proline endopept, Staph Protease, Trypsin K, AspN
	RISNCVADY	1.07	No Mutation	− 0.20	0.00	1040.27	Chymotrypsin, Cyanogen Bromide, IodosoBenzoate, Proline endopept, Staph Protease, Trypsin K
	CVADYSVLY	1.18	No Mutation	0.11	1.00	1032.29	Trypsin, Clostripain, Cyanogen Bromide, IodosoBenzoate, Proline endopept, Staph Protease, Trypsin K, Trypsin R
	FTNVYADSF	1.03	No Mutation	0.03	-1.00	10,632.24	Trypsin, Clostripain, Cyanogen Bromide, IodosoBenzoate, Proline endopept, Staph Protease, Trypsin K, Trypsin R
Helper T-cells epitopes	YFPLQSYGF	1.0799	No Mutation	− 1.21	0.00	1121.38	Trypsin, Clostripain, Cyanogen Bromide, IodosoBenzoate, Staph Protease, Trypsin K, Trypsin R, AspN
	VIAWNSNNL	1.0091	No Mutation	− 0.90	0.00	1030.28	Trypsin, Clostripain, Cyanogen Bromide, Proline endopept, IodosoBenzoate, Staph Protease, Trypsin K, Trypsin R, AspN
	YSVLYNSAS	1.09	No Mutation	− 0.81	0.00	1003.19	Trypsin, Clostripain, Cyanogen Bromide, Proline endopept, IodosoBenzoate, Staph Protease, Trypsin K, Trypsin R, AspN