Fig. 1.

Effect of ginsenoside Rg3 on AHR and cell counts in BALF from asthmatic mice. (A) Experimental procedures for asthmatic mouse studies. (B) Inflammatory cells in BALF were counted. (C) Mice inhaled increasing doses of methacholine, and AHR was assessed and is shown as Penh values. (D) AHR was measured as a percentage from the baseline level of lung resistance (RI). Three independent experiments were analyzed, and all data are presented as the mean ± SEM. ∗p < 0.05 and ∗∗p < 0.01 compared with the OVA control group. Mice were divided into normal (N), OVA-sensitized mice (OVA), 5 mg/kg prednisolone control (P), 5 mg/kg ginsenoside Rg3 (Rg5) and 10 mg/kg ginsenoside Rg3 (Rg10) groups. IP, intraperitoneal injection; IH, inhalation.