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. 2021 Oct 15;11(10):4788–4806.

Figure 7.

Figure 7

DKK1 increased angiogenesis and EMT markers in the xenograft mouse model. A. Observation of IF staining for DKK1, VEGFR2 and CD31 on serial paraffin sections of xenograft tumors generated using Hep3B wild-type and CRISPR#73 with confocal microscopy. B. Quantification of DKK1 (P<0.05), VEGFR2 (P<0.05) and CD31 (P<0.05) IF, presented as the mean fluorescence intensity. C. Observation of IF staining for vimentin, fibronectin and E-cadherin on serial paraffin sections of xenograft tumors generated using Hep3B wild-type and CRISPR#73 cells with confocal microscopy. D. Quantification of vimentin (P<0.05), fibronectin (P<0.01) and E-cadherin (P<0.05) IF, presented as the mean fluorescence intensity.