DKK1 increased angiogenesis and EMT markers in the transgenic mouse model. A. Observation of IF staining for DKK1, VEGFR2 and CD31 on serial paraffin sections of HI_Luc2A and HI_DKK1 tumors using confocal microscopy. B. Quantification of DKK1, VEGFR2 and CD31, presented as the mean fluorescence intensity. C. IF staining for vimentin, fibronectin and E-cadherin on serial paraffin sections of HI_Luc2A and HI_DKK1 tumors. D. Quantification of vimentin, fibronectin and E-cadherin, presented as the mean fluorescence intensity.