Table 4.
Cox regression of risk factors associated with recurrence in CR patients after first TACE
| Predictor Variables | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (per year increase) | 0.997 | 0.979-1.015 | 0.721 | |||
| Male (vs. female) | 1.053 | 0.681-1.628 | 0.818 | |||
| Body weight loss (vs. no) | 0.744 | 0.302-1.833 | 0.521 | |||
| Viral infection (vs. non-viral) | 1.556 | 0.782-3.098 | 0.208 | |||
| DM (vs. no) | 1.425 | 0.933-2.178 | 0.101 | |||
| CTP class B (vs. A) | 0.741 | 0.384-1.430 | 0.372 | |||
| Beyond up-to-7 criteria (vs. within) | 1.455 | 0.735-2.923 | 0.277 | |||
| Bilobar tumor extent (vs. unilobar) | 1.415 | 0.853-2.345 | 0.179 | |||
| Macrovascular invasion (vs. no) | 2.264 | 1.091-4.700 | 0.028 | 2.084 | 1.000-4.345 | 0.050 |
| AAR≥1.7 (vs. <1.7) | 0.703 | 0.374-1.319 | 0.272 | |||
| AFP≥15 ng/ml (vs. <15 ng/ml) | 1.675 | 1.104-2.541 | 0.015 | 1.628 | 1.071-2.474 | 0.023 |
| Platelet≥150 K/μL (vs. <150 K/μL) | 0.752 | 0.453-1.247 | 0.269 | |||
| Fever after 1st TACE (vs. no) | 0.622 | 0.364-1.062 | 0.081 | |||
Abbreviations: AAR, aspartate aminotransferase to alanine aminotransferase ratio; AFP, alpha-fetoprotein; CTP, Child-Turcotte-Pugh; DM, diabetes mellitus; TACE, transarterial chemoembolization.