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. 2021 Oct 13;7(10):e08172. doi: 10.1016/j.heliyon.2021.e08172

Figure 5.

Figure 5

Pre/post-treatment effect of KSM-66 on several enzymes in SH-SY5Y cell lysate. In pre-treatment, the KSM-66 extract was added 24 h prior to 6-OHDA exposure. Pre-treatment effects are shown for (A) glutathione peroxidase (GPx), (B) thiol transferase and (C) CDNB activities. In the post-treatment study, the KSM-66 extract was added 24 h after exposure to 6-OHDA. The post-treatment study show 6-OHDA reduces glutathione peroxidase (GPx) (D), thiol transferase (E) and CDNB (F) activities, whereupon KSM-66 increases their activity. Bar graphs shows mean ± SEM of GPx, thiol transferase and CDNB activities of all groups. The values are presented as mean ± SEM. Data were analyzed by One-way ANOVA with Bonferroni's Multiple Comparison test; ∗p < 0.05 represents significant differences compared to the control; +p < 0.05 represents significant differences compared to 6-OHDA exposed cells; #p < 0.05 represents significant differences compared to 1 mg/ml exposed cells; ˆp < 0.05 represents significant differences compared to 0.75 mg/ml exposed cells.