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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Vascul Pharmacol. 2021 Jun 9;139:106881. doi: 10.1016/j.vph.2021.106881

Figure 5. Angiotensin-II induces endothelial dysfunction and high blood pressure dependent on inflammasome.

Figure 5.

Concentration-response curves were performed to acetylcholine (ACh) (A) and to sodium nitroprusside (SNP) (B) in segments of mesenteric arteries (2nd order). (C) Systolic blood pressure measured by tail plestimography.from Ctrl (WT) and Casp1−/− mice treated with Ang-II (490 ng/min/kg for 14 days with ALZET osmotic minipumps). N = 4 to 7. *P<0.05 vs. WT; #P<0.05 vs. Ang-II and Casp-1 groups.