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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Vascul Pharmacol. 2021 Jun 9;139:106881. doi: 10.1016/j.vph.2021.106881

Figure 8. Angiotensin-II induces vascular proliferation and increases TGF-β via inflammasome.

Figure 8.

Cell counting kit-8 (CCK-8) (A), proliferating cell nuclear antigen (PCNA) protein expression (B) and Ki67 (C) and TGF-β (D) gene expressions in Rat Aortic Vascular Smooth Muscle Cells (RASMC) incubated with Ang-II (0,1 μM) for 8 h or 24 h. TGF-β (E) gene expressions in RASMC incubated with IL-1β (5ng/mL) for 8 h or 24 h. Some experiments were performed in the presence of a selective NLRP3 antagonist (MMC950, 1 μM, 30 min). N = 4 to 6. Values are reported as mean ± s.e.m. *P<0.05 vs. vehicle.