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. 2021 Oct 27;24(6):871. doi: 10.3892/mmr.2021.12511

Table II.

Cell types commonly used in atherosclerosis research.

Cell type Commonly used primary cells Commonly used cell lines Application
Endothelial cell Human umbilical vein endothelial cells; human microvascular endothelial cells Endothelial cell dysfunction; inflammatory response
Macrophage Peritoneal macrophages Bone marrow-derived macrophages THP1, J774a.1 and U937 Phagocytosis; proliferation; migration; adhesion; polarization
Smooth muscle cell Vascular smooth muscle cells from rat; vascular smooth muscle cells from mice A7r5 and MOVAS-1 Calcification; phenotype transformation; proliferation; migration