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. 2021 Oct 21;23(10):e27714. doi: 10.2196/27714

Figure 5.

Figure 5

DRIP scores calculated using side effect severity and frequency. (A) DRIP scores (x-axis) for ATC classification system groups (y-axis) ordered by median severity with outliers labeled. The dashed blue line indicates the median DRIP score of 0.439 across all drugs. (B) DRIP scores (x-axis) for opioid class drugs (y-axis), as denoted by the N02A ATC group. Fentanyl, an extremely potent synthetic opioid, is ranked first as having the most severe side effect. (C) DRIP scores (x-axis) for statins (y-axis), as denoted by the C10AA ATC group. Atorvastatin, the strongest statin in broad use, is ranked to have the most severe side effect, whereas lower-efficacy statins are ranked as having less-severe side effects. ATC: Anatomical Therapeutic Chemical; DRIP: drug-risk profile.