. 2021 Oct 15;12(21):4090–4112. doi: 10.1021/acschemneuro.1c00485

Table 3. Inhibition Mechanisms Determined on EeAChE and eqBChE, Inhibition Constants (K_i), and α Values.

	EeAChE					eqBChE
cmpd	mechanism	K_i ± SD^a (μM)	R²	α	cmpd	mechanism	K_i ± SD^a (μM)	R²	α
9	mixed	0.312 ± 0.108	0.982	7.5	18	mixed	3.034 ± 0.604	0.986	7.3
13	mixed	0.426 ± 0.132	0.991	0.3	22	mixed	0.099 ± 0.071	0.990	10
19	uncomp.	0.509 ± 0.018	0.992		25	mixed	2.373 ± 0.304	0.992	2.2
23	mixed	0.743 ± 0.316	0.983	2.2	26	mixed	3.465 ± 1.480	0.950	0.5
25	mixed	0.995 ± 0.374	0.988	0.8	28	mixed	3.434 ± 0.701	0.988	0.8
28	mixed	1.323 ± 0.622	0.990	1.2	30	mixed	1.105 ± 0.189	0.983	1.4

Each data was obtained with three substrate and five inhibitor concentrations; each measurement was carried out in five replicates (see the Experimental Section).

Table 3. Inhibition Mechanisms Determined on EeAChE and eqBChE, Inhibition Constants (Ki), and α Values.

Table 3. Inhibition Mechanisms Determined on EeAChE and eqBChE, Inhibition Constants (K_i), and α Values.